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<DIV><FONT size=2>La Secretaría Académica invita a l</FONT><FONT size=2>a
charla presentada por el Dr Terry Speed, Director de Bioinformatics Division,
Walter and Eliza Hall Institute of Medical Research, Melbourn-Australia y
Profesor Emérito del Departamento de Estadística de la Universidad de
California, Berkeley- USA.<BR></FONT><FONT size=2>El Dr. Terry Speed es
mundialmente conocido por sus contribuciones en bioinformatica en especial en el
análisis de datos de experimentos de microarreglos.<BR></FONT></DIV>
<DIV><FONT size=2>Resumen de la charla<BR>For the past decade, microarrays have
been the assays of choice for a wide range of high-throughput biological assays.
Recent improvements in the efficiency, quality, and cost of DNA sequencing are
prompting biologists rapidly to abandon microarrays in favor of so-called
next-generation sequencers, e.g., Applied Biosystems' SOLiD, Helicos
BioSciences' HeliScope, Illumina's Genome Analyzer, and Roche's 454 Life
Sciences sequencing systems. These high-throughput sequencing technologies have
already been applied to studying genome-wide transcription levels (mRNA-Seq),
transcription factor binding sites (ChIP-Seq), chromatin structure, DNA
methylation status, copy number and several other tasks. Such studies have
overcome many longstanding limitations of microarray-based studies, but of
course new technologies raise similar as well as novel statistical and
computational challenges. In this talk I'll introduce the topic and outline some
of the issues that are currently interesting me in this
area.<BR> <BR>Lugar: Aula 6 Pabellón II. FCEN-UBA<BR>Fecha: 10 de Marzo
2010<BR>Horario: 17 hs.<BR>Para los investigadores que deseen tener una
entrevista personal con el Dr. Terry Speed, por favor comunicarse con la
Secretaría de la Carrera de Especiañización en Estadística para Ciencias de la
Salud: </FONT><A href="mailto:ceecs@fcen.uba.ar"><FONT
size=2>ceecs@fcen.uba.ar</FONT></A><BR><FONT size=2>Dra. Diana M.
Kelmansky<BR>Directora Adjunta<BR>Instituto de Cálculo<BR>FCEN- UBA</FONT></DIV>
<DIV><FONT size=2></FONT> </DIV>
<DIV><FONT size=2></FONT> </DIV>
<DIV><FONT size=2>Saludos cordiales,</FONT></DIV>
<DIV><FONT size=2>Secretaría Académica</FONT></DIV>
<DIV><FONT size=2></FONT> </DIV>
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