[Todos] seminario LFBM 18/3

[Omar Adrian Coso]

SEMINARIO LFBM

Dr. Uri Saragovi

Pharm. and Ther. Oncology
Cancer Center
Lady Davis Institute
Jewish General Hospital
Montreal
Quebec - CANADA

JUEVES 18/3 13 HS.
AULA DE SEM. LFBM

El Dr. Saragovi tiene la intención de contactarse con estudiantes y
graduados como potenciales candidatos a practicar ciencia en su
laboratorio. Contactarse por mail a <ocoso at fbmc.fcen.uba.ar>

"Peptidomimicry in basic
receptor pharmacology research,
 and in drug discovery for
neuroscience and cancer"

Peptidomimicry reduces large polypeptides into small functional units,
preferabily organic small molecules with agonistic or antagonistic
properties. Peptidomimicry requires the rational design and synthesis of
small molecule compounds, followed by binding and biological assays
where the pharmacological, cell biological and functional properties of
the compounds are characterized.
The initial "hits" can be used as fine probes for basic science and
receptor biology studies, while second generation improved
peptidomimetics can be used as "drug leads" in experimental medicine.
The evolution of receptor-specific agonistic or antagonistic
peptidomimetics developed in the Saragovi laboratory will be discussed,
followed by the application of these agents in animal models of
neurodegenerative disorders or cancer.


OMAR ADRIAN COSO Ph.D.
Laboratorio de Fisiologia y Biologia Molecular.
Facultad de Ciencias Exactas y Naturales.
Universidad de Buenos Aires.

Address:
LFBM. Ciudad Universitaria.
Pabellon II. Piso 2.
1428 Buenos Aires
ARGENTINA

Phone: 54-11-4-576-3368/3386.
Fax: 54-11-4-576-3321.